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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF9
All Species:
10.61
Human Site:
S412
Identified Species:
21.21
UniProt:
O60383
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60383
NP_005251.1
454
51444
S412
I
I
Y
E
K
L
D
S
S
V
P
R
P
S
C
Chimpanzee
Pan troglodytes
XP_527008
455
51476
S413
I
I
Y
E
K
L
D
S
S
V
P
R
P
S
C
Rhesus Macaque
Macaca mulatta
XP_001101902
271
31418
R230
E
D
A
A
E
D
G
R
S
S
H
H
R
H
R
Dog
Lupus familis
XP_549005
393
44984
S352
V
N
E
L
V
D
Q
S
V
P
Q
P
S
C
V
Cat
Felis silvestris
Mouse
Mus musculus
Q07105
441
49630
P399
I
I
Y
E
K
L
D
P
S
V
P
R
P
S
C
Rat
Rattus norvegicus
P49001
393
44364
K352
L
V
N
S
V
N
S
K
I
P
K
A
C
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510645
359
41050
T318
V
N
E
R
V
N
R
T
V
P
R
P
C
C
V
Chicken
Gallus gallus
Q90752
405
46039
S364
L
V
N
S
V
N
S
S
I
P
K
A
C
C
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P85857
404
46271
S363
M
N
S
M
D
P
N
S
T
P
P
S
C
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
G546
L
V
N
N
M
N
P
G
K
V
P
K
A
C
C
Honey Bee
Apis mellifera
XP_001122815
374
42068
S332
L
V
Y
S
T
K
P
S
M
V
P
K
A
C
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
A354
V
N
S
I
D
N
R
A
V
P
K
V
C
C
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
50
28.6
N.A.
72
21.5
N.A.
26.4
21.8
N.A.
21.1
N.A.
21.7
21.3
N.A.
20.2
Protein Similarity:
100
99.1
54.1
45.1
N.A.
80.6
39.2
N.A.
44.2
38.3
N.A.
39.6
N.A.
36.9
40.3
N.A.
39.4
P-Site Identity:
100
100
6.6
6.6
N.A.
93.3
0
N.A.
0
6.6
N.A.
13.3
N.A.
20
33.3
N.A.
0
P-Site Similarity:
100
100
13.3
13.3
N.A.
93.3
13.3
N.A.
13.3
20
N.A.
33.3
N.A.
40
53.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
0
9
0
0
0
17
17
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
42
67
42
% C
% Asp:
0
9
0
0
17
17
25
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
17
25
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% H
% Ile:
25
25
0
9
0
0
0
0
17
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
25
9
0
9
9
0
25
17
0
0
0
% K
% Leu:
34
0
0
9
0
25
0
0
0
0
0
0
0
0
0
% L
% Met:
9
0
0
9
9
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
34
25
9
0
42
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
17
9
0
50
50
17
25
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
17
9
0
0
9
25
9
0
9
% R
% Ser:
0
0
17
25
0
0
17
50
34
9
0
9
9
25
0
% S
% Thr:
0
0
0
0
9
0
0
9
9
0
0
0
0
0
0
% T
% Val:
25
34
0
0
34
0
0
0
25
42
0
9
0
0
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _